Remote(SocketError)

Exchange 2016 receiving error message: "Message or connection acked with status Retry and response 441 4.4.1 Error encountered while communicating with primary target IP address: ""Failed to connect. Winsock error code: 10061, Win32 error code: 10061."" Attempted failover to alternate host, but that did not succeed. Either there are no alternate hosts, or delivery failed […]